Scanning Probe Microscopy with Integrated Biosensors

نویسندگان

  • Angelika Kueng
  • Christine Kranz
  • Boris Mizaikoff
چکیده

Sensor devices including biosensors are attracting considerable interest for molecule-speciŽ c measurements with high sensitivity in a variety of applications ranging from clinical and pharmaceutical analysis to industrial process monitoring and environmental surveillance applications. A biosensor is composed of two main components: (i) a sensing interface, which speciŽ cally interacts with analyte molecules, creating a change in physical or chemical parameters (e.g., pH, redox state, temperature, charge, refractive index, etc.) and (ii) a transducer, which converts this information into a quantiŽ able read-out signal. Most commonly, electrochemical, optical, mass sensitive, and thermosensitive transducers are applied for biosensing platforms. Per its deŽ nition, the biological recognition element is in direct contact with the transducer surface. Following transduction, the signal is typically Ž ltered, ampliŽ ed, recorded, or transmitted by a read-out system, resulting in a Scanning Probe Microscopy with Integrated Biosensors

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Scanning impedance microscopy (SIM): A novel approach for AC transport imaging

Scanning Impedance Microscopy (SIM) is one of the novel scanning probe microscopy (SPM) techniques, which has been developed to taking image from sample surface, providing quantitative information with high lateral resolution on the interface capacitance, and investigating the local capacitance–voltage (C–V) behavior of the interface and AC transport properties. The SIM is an ordinary AFM equip...

متن کامل

Scanning hall probe microscopy technique for investigation of magnetic properties

Scanning Hall Probe Microscopy (SHPM) is a scanning probe microscopy technique developed to observe and image magnetic fields locally. This method is based on application of the Hall Effect, supplied by a micro hall probe attached to the end of cantilever as a sensor.  SHPM provides direct quantitative information on the magnetic state of a material and can also image magnetic induction under a...

متن کامل

Electrospun polylactic acid nanofiber membranes as substrates for biosensor assemblies

Biotin has been successfully incorporated into polylactic acid (PLA) nanofibers through electrospinning to prepare membrane substrates for biosensors based on biotin–streptavidin specific binding. Biotin incorporated PLA nanofiber membranes were characterized with scanning electron microscopy (SEM), electron probe microanalysis (EPMA), and confocal microscopy. Under optimized conditions, small ...

متن کامل

Scanning hall probe microscopy technique for investigation of magnetic properties

Scanning Hall Probe Microscopy (SHPM) is a scanning probe microscopy technique developed to observe and image magnetic fields locally. This method is based on application of the Hall Effect, supplied by a micro hall probe attached to the end of cantilever as a sensor.  SHPM provides direct quantitative information on the magnetic state of a material and can also image magnetic induction under a...

متن کامل

Scanning impedance microscopy (SIM): A novel approach for AC transport imaging

Scanning Impedance Microscopy (SIM) is one of the novel scanning probe microscopy (SPM) techniques, which has been developed to taking image from sample surface, providing quantitative information with high lateral resolution on the interface capacitance, and investigating the local capacitance–voltage (C–V) behavior of the interface and AC transport properties. The SIM is an ordinary AFM equip...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2004